6 x Pharmaceutical Anastrozole/Adex 1mg x 28

Description

Classification

6 x Pharmaceutical Anastrozole/Adex 1mg x 28 contains anastrozole, an aromatase inhibitor and prescription-only medicine used in the UK primarily for hormone receptor-positive breast cancer in postmenopausal women. Each tablet contains 1mg of anastrozole. By reducing the body’s production of oestrogen, anastrozole helps limit the hormonal stimulation of certain breast cancers. UK product information also includes its use as an adjuvant treatment and, for appropriately selected postmenopausal women, primary prevention of breast cancer where the risk is moderate or high.

What is 6 x Pharmaceutical Anastrozole/Adex 1mg x 28?

6 x Pharmaceutical Anastrozole/Adex 1mg x 28 is a presentation containing six packs of 28 tablets, with each tablet providing 1mg of anastrozole. Anastrozole belongs to the aromatase inhibitor family and is designed to reduce circulating oestrogen levels after the menopause. It is particularly relevant where a breast cancer is hormone receptor-positive and responds to reduced oestrogen stimulation. As a prescription-only medicine, its suitability should be assessed by a qualified healthcare professional before treatment is started.

Dosage

For approved adult indications, the usual UK dose of anastrozole is one 1mg tablet once daily, although the exact treatment plan and duration should always be determined by the prescribing clinician. The tablet should be swallowed whole with water and may be taken with or without food. Patients who forget a dose should generally skip the missed dose rather than taking two tablets together. Treatment for early breast cancer is commonly continued for several years, with the exact duration determined by the specialist managing the individual patient’s care.

How Does 6 x Pharmaceutical Anastrozole/Adex 1mg x 28 Work?

Anastrozole works by reducing the amount of oestrogen produced in the body. After menopause, much of the body’s oestrogen is produced when the enzyme aromatase converts other hormones into oestrogen. By inhibiting aromatase, anastrozole lowers oestrogen availability. For hormone-sensitive breast cancer, this reduction can help slow or prevent the growth of cancer cells that depend on oestrogen signalling.

Benefits

When prescribed for an appropriate patient, anastrozole offers an established hormone-treatment option for postmenopausal women with hormone receptor-positive breast cancer. Its main clinical benefits include:

• Helping reduce oestrogen stimulation of hormone-sensitive breast cancer.
• Supporting treatment of hormone receptor-positive early invasive breast cancer.
• Providing an option for advanced hormone receptor-positive breast cancer.
• Helping reduce the risk of recurrence when used as prescribed after other breast cancer treatment.
• Providing a preventive treatment option for selected postmenopausal women at moderate or high risk of developing breast cancer.

When Should You Not Take 6 x Pharmaceutical Anastrozole/Adex 1mg x 28?

Anastrozole should not be taken by people with a known allergy to anastrozole or any of its ingredients, and it is contraindicated during pregnancy and breastfeeding. It is generally intended for postmenopausal women for its licensed breast-cancer indications and is not recommended for children or adolescents. It should also be discussed carefully with a clinician if there is a history of osteoporosis, liver or kidney problems, heart disease or stroke, as reduced oestrogen can affect bone health and other existing conditions.

What is the Mechanism of 6 x Pharmaceutical Anastrozole/Adex 1mg x 28?

The active ingredient, anastrozole, is a selective aromatase inhibitor. Aromatase is an enzyme involved in converting androgens into oestrogens, particularly after menopause. By inhibiting this enzyme, anastrozole substantially lowers circulating oestrogen levels. This hormonal action is central to its effectiveness in hormone receptor-positive breast cancer, where reducing oestrogen exposure can help control tumour growth and reduce the likelihood of recurrence.

Uses of 6 x Pharmaceutical Anastrozole/Adex 1mg x 28

Anastrozole has several established clinical uses in postmenopausal women. These include treatment of hormone receptor-positive advanced breast cancer and adjuvant treatment of hormone receptor-positive early invasive breast cancer. It may also be prescribed after two to three years of adjuvant tamoxifen as part of a longer endocrine-treatment programme. Current UK product information also permits primary prevention in appropriately selected postmenopausal women at moderate or high risk, where treatment is initiated and monitored by an experienced medical practitioner.

Warnings and Precautions for 6 x Pharmaceutical Anastrozole/Adex 1mg x 28

Anastrozole should be used under appropriate medical supervision because lowering oestrogen can produce important effects throughout the body. Particular attention should be given to:

• Bone health: long-term treatment can reduce bone mineral density and increase fracture risk.
• Liver function: caution is advised in moderate or severe hepatic impairment.
• Kidney function: severe renal impairment requires careful clinical consideration.
• Other medicines: tamoxifen and oestrogen-containing treatments can reduce the pharmacological effect of anastrozole.
• Menopausal status: treatment should not be assumed appropriate for people who are still premenopausal.

Bone-density assessment may be appropriate for women with osteoporosis or an increased risk of bone loss.

Side Effects of 6 x Pharmaceutical Anastrozole/Adex 1mg x 28

Like all prescription medicines, anastrozole can cause side effects, although not everyone experiences them. Common effects can resemble menopausal symptoms and include hot flushes, sweating, tiredness, sleep difficulties, low mood, nausea and aches or pains affecting the muscles and joints. Because reduced oestrogen can weaken bones, osteoporosis and an increased risk of fractures are important longer-term considerations. Patients experiencing persistent, severe or unusual symptoms should speak with their doctor, pharmacist or breast-care team.

Storage for 6 x Pharmaceutical Anastrozole/Adex 1mg x 28

Keep anastrozole in its original packaging and store it according to the instructions supplied with the specific medicine. Tablets should be kept securely away from children and protected from unsuitable environmental conditions. Do not use tablets if the packaging is damaged or the medicine has passed its expiry date. As with other prescription medicines, unused or unwanted tablets should be returned to a pharmacy for safe disposal rather than placed in household waste or flushed down a toilet.

Where to buy 6 x Pharmaceutical Anastrozole/Adex 1mg x 28?

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Frequently Asked Questions

1. What is anastrozole used for?

Anastrozole is mainly used to treat hormone receptor-positive breast cancer in postmenopausal women. It can also be used as adjuvant treatment and, for selected women, to reduce the risk of developing breast cancer.

2. What is the usual strength of anastrozole tablets?

UK anastrozole tablets commonly contain 1mg of anastrozole. The usual adult dose for licensed indications is one 1mg tablet once daily, as prescribed by a healthcare professional.

3. Can anastrozole be taken during pregnancy?

No. Anastrozole is contraindicated during pregnancy and breastfeeding. Anyone who could be pregnant should discuss this with their doctor before taking the medicine.

4. Does anastrozole affect bone health?

Yes. By lowering oestrogen, anastrozole can reduce bone mineral density and increase the risk of osteoporosis and fractures. Bone-density monitoring may therefore be recommended for people at increased risk.

5. Is anastrozole available without a prescription in the UK?

No. Anastrozole is classified as a prescription-only medicine in UK medicines information, so it should be obtained through an appropriate regulated healthcare and pharmacy service.